The most ambitious form of treatment for AMN patients
to date is the quantification of movement impairments.
purpose of this study is to measure the time course
of sensory loss and weakness and evaluate treatments
in people with AMN. This is being done through
the development of tests that are sensitive enough
to detect defecits and track small changes in
sensation and strength over 6 months to a year.
Secondly, the further aim is to determine the
relative contributions of sensory loss and weakness
to balance and walking. Previously, doocumentation
of AMN progression relied upon clinical observations
and subjective rating scales that required 4 to
5 years to show change. This has made it difficult
to evaluate small changes in sensation and strength,
and has delayed assessment of therapeutic interventions... » View Study